R C Gupta, et al. Journal of Animal Physiology and Animal Nutrition, 770-777 (2012) Link to Abstract
Subjects: Arthritic dogs
Time Period: 150 days
Methodology: Four groups
- Group 1–No UC-II®, no Glucosamine, no Chondroitin
- Group 2–UC-II® only at 10mg/day
- Group 3–Glucosamine and Chondroitin only (2000mg/day and 1600mg/day respectively)
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Group 4–UC-II®, Glucosamine and Chondroitin (10mg/day, 2000mg/day and 1600mg/day respectively)
Findings:
- No changes in Group 1.
- Group 2, 3 and 4 saw significant reductions in overall pain, pain upon limb manipulation and pain after exercise, all based on physical exam and observation.
- Only Group 2 (UC-II® only) saw pain reduction based on Ground Force Plate (GFP) analysis. GFP is a scientific measure that gauges the downforce of a dog’s limbs while running. The greater the downforce, the less pain experienced.
- There were no adverse effects from any of the ingredients.
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